Balakrishnan V, Lim A S, Low C H, Lee C P, Tseng P S, Chan W K, Chan T K, Tan J, Tan D
Department of Ophthalmology, National University of Singapore.
Singapore Med J. 1993 Aug;34(4):309-12.
Myopia is a national epidemic in Singapore. Photorefractive Keratectomy (PRK) for the treatment of myopia using the Argon Fluoride Excimer Laser commenced in January 1992 at the Singapore National Eye Centre.
An open, prospective, non randomised clinical trial to assess the efficacy, predictability, stability, and safety of PRK for the correction of myopia between -2.0 to -6.0 dioptres.
One hundred and fifty-five eyes of one hundred and thirty-five patients underwent PRK between January and September 1992, of which thirty-one had completed at least six months of follow-up. Twenty-nine of the thirty-one patients (93.5%) achieved an unaided visual acuity of at least 6/12. Twenty-six patients (83.9%) were within 1 dioptre of emmetropia. There was an initial over-correction in all patients which regressed to a plateau at around three or four months. Corneal haze did not pose a significant problem. Three patients had ocular hypertension, and another developed a mild allergic reaction to the antibiotic-steroid ointment.
Excimer Laser Photorefractive Keratectomy is a very effective, fairly predictable, stable and safe surgical method for the treatment of myopia.
近视在新加坡是一种全国性的流行病。1992年1月，新加坡国立眼科中心开始使用氟化氩准分子激光进行光性屈光性角膜切削术（PRK）治疗近视。
一项开放、前瞻性、非随机临床试验，以评估PRK矫正-2.0至-6.0屈光度近视的疗效、可预测性、稳定性和安全性。
1992年1月至9月期间，135例患者的155只眼睛接受了PRK治疗，其中31例完成了至少6个月的随访。31例患者中有29例（93.5%）裸眼视力至少达到6/12。26例患者（83.9%）屈光不正度数在正视眼1屈光度范围内。所有患者最初均有过矫，在大约三四个月时恢复到平稳状态。角膜 haze 不是一个严重问题。3例患者出现眼压升高，另1例对抗生素 - 类固醇眼膏发生轻度过敏反应。
准分子激光光性屈光性角膜切削术是一种治疗近视非常有效、相当可预测、稳定且安全的手术方法。
