Lucertini M, Ciniglio Appiani G, Antonini R, Urbani L
Italian Air Force, DASRS Aerospace Medicine Department, Pratica di Mare AFB, Rome.
Audiology. 1993 Nov-Dec;32(6):356-62. doi: 10.3109/00206099309071866.
The aim of the present paper was the investigation of middle-latency responses (MLRs) and steady-state responses (SSRs) during and after a 30-min exposure to hypobaric hypoxia (5182 m above sea level). The test was performed in a hypobaric chamber on 8 male audiologically normal volunteers. The auditory stimulus (500-Hz tone burst), delivered at rates of 10 and 40/s for MLRs and SSRs, respectively, was recalibrated in the hypobaric condition because of the reduced air density. Absolute latencies of waves Na and Pa and their interpeak amplitude were the MLR parameters investigated; for the SSRs, the first positive wave (P1) absolute latency and the interpeak amplitude between P1 and the first negative wave (N1) were considered. The results showed an absence of statistically significant modification of the MLRs. On the contrary, the SSRs showed a significant (p < 0.025) latency increase during hypoxia, with an immediate recovery upon return to ground level. No significant changes of SSR amplitudes were observed. One possible data interpretation is related to the higher stimulation rate adopted for the SSRs; a second possibility could be a different electrogenesis between MLRs and SSRs.
本文的目的是研究在30分钟低压缺氧（海拔5182米）期间及之后的中潜伏期反应（MLR）和稳态反应（SSR）。该测试在低压舱中对8名听力正常的男性志愿者进行。由于空气密度降低，在低压条件下对分别以10次/秒和40次/秒的速率传递给MLR和SSR的听觉刺激（500赫兹短音）进行了重新校准。研究的MLR参数为Na波和Pa波的绝对潜伏期及其峰间振幅；对于SSR，考虑了第一个正波（P1）的绝对潜伏期以及P1与第一个负波（N1）之间的峰间振幅。结果显示MLR没有统计学上的显著变化。相反，SSR在缺氧期间显示出显著（p < 0.025）的潜伏期增加，回到地面水平后立即恢复。未观察到SSR振幅的显著变化。一种可能的数据解释与SSR采用的较高刺激速率有关；第二种可能性可能是MLR和SSR之间的电发生不同。
