Urbani L, Lucertini M
Italian Air Force, DASRS, Aerospace Medicine Department, Pratica di Mare AFB, Rome, Italy.
Hear Res. 1994 Jun 1;76(1-2):73-7. doi: 10.1016/0378-5955(94)90089-2.
Auditory brainstem responses (ABRs) were recorded in six volunteers before, during and after 90-min exposure to hypobaric hypoxia (5,184 m; barometric pressure = 405 mmHg) in an altitude chamber. Waves I, III and V absolute and interpeak latencies were analysed. The main result of the experiment was a significant shortening of the brainstem transmission time (I-V interval) in the recovery from hypoxia compared with the basal condition. This finding could be explained with a slow decay of the compensatory mechanisms acting during hypoxia and/or a transient neuronal hyperexcitability at the end of the hypoxic stress.
在海拔舱中，对6名志愿者在90分钟低压低氧暴露（5184米；气压 = 405 mmHg）前、暴露期间和暴露后记录听觉脑干反应（ABR）。分析了I、III和V波的绝对潜伏期和峰间潜伏期。实验的主要结果是，与基础状态相比，缺氧恢复过程中脑干传导时间（I-V间期）显著缩短。这一发现可以用缺氧期间起作用的代偿机制的缓慢衰减和/或缺氧应激结束时短暂的神经元过度兴奋来解释。
