使用明显均一的大鼠肝脏细胞色素P - 450制剂对硫代磷酸O,O - 二乙基 - O - 对硝基苯基酯（对硫磷）和苄非他明代谢的研究：细胞色素P - 450抗体制剂的作用 - Suppr

Suppr

超能文献

Studies of the metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) and benzphetamine using an apparently homogeneous preparation of rat liver cytochrome P-450: effect of a cytochrome P-450 antibody preparation.

作者信息

Kamataki T, Belcher D H, Neal R A

出版信息

Mol Pharmacol. 1976 Nov;12(6):921-32.

PMID:826783

Abstract

摘要

相似文献

Studies of the metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) and benzphetamine using an apparently homogeneous preparation of rat liver cytochrome P-450: effect of a cytochrome P-450 antibody preparation.使用明显均一的大鼠肝脏细胞色素P - 450制剂对硫代磷酸O,O - 二乙基 - O - 对硝基苯基酯（对硫磷）和苄非他明代谢的研究：细胞色素P - 450抗体制剂的作用

Mol Pharmacol. 1976 Nov;12(6):921-32.

Comparison of the metabolism of parathion by a rat liver reconstituted mixed-function oxidase enzyme system and by a system containing cumene hydroperoxide and purified rat liver cytochrome P-450.大鼠肝脏重组混合功能氧化酶系统与含氢过氧化异丙苯和纯化大鼠肝脏细胞色素P - 450的系统对硫磷代谢的比较。

Drug Metab Dispos. 1977 Mar-Apr;5(2):191-7.

Metabolism of diethyl p-nitrophenyl phosphorothionate (parathion) by a reconstituted mixed-funcion oxidase enzyme system: studies of the covalent binding of the sulfur atom.对硫磷（对硝基苯基硫代磷酸二乙酯）在重组混合功能氧化酶系统中的代谢：硫原子共价结合的研究

Mol Pharmacol. 1976 Nov;12(6):933-44.

Studies of the metabolism of parathion with an apparently homogeneous preparation of rabbit liver cytochrome P-450.利用兔肝细胞色素P - 450的一种明显均一的制剂对对硫磷代谢进行的研究。

Drug Metab Dispos. 1976 Mar-Apr;4(2):180-9.

Preparation and properties of highly purified cytochrome p-450 and NADPH-cytochrome P-450 reductase from pulmonary microsomes of untreated rabbits.从未经处理的家兔肺微粒体中制备高纯度细胞色素P-450和NADPH-细胞色素P-450还原酶及其性质

Mol Pharmacol. 1977 Sep;13(5):911-23.

Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.苯丙胺连续氧化过程中组成型和苯巴比妥诱导的细胞色素P-450同工酶的相互作用。对未处理和苯巴比妥处理大鼠微粒体中苯丙胺诱导的过氧化氢产生和455纳米复合物形成差异的解释。

Mol Pharmacol. 1983 May;23(3):748-57.

Differential effects of proteinase K on the components of the liver microsomal cytochrome P-450 mixed function oxidase system.蛋白酶K对肝脏微粒体细胞色素P - 450混合功能氧化酶系统各组分的不同作用。

Drug Metab Dispos. 1991 Nov-Dec;19(6):1016-21.

Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).对硫代磷酸O,O-二乙基对硝基苯酯（对硫磷）混合功能氧化酶催化代谢过程中释放的硫与对氧磷结合的研究。

Biochem Pharmacol. 1974 Jun 15;23(12):1733-44. doi: 10.1016/0006-2952(74)90400-6.

Multiple forms of ethoxyresorufin O-de-ethylase and benzphetamine N-demethylase in solubilized and partially resolved rat liver cytochromes P-450.溶解并部分分离的大鼠肝脏细胞色素P-450中乙氧试卤灵O-脱乙基酶和苄非他明N-脱甲基酶的多种形式

Drug Metab Dispos. 1979 May-Jun;7(3):188-93.

Metabolism of thioacetamide and thioacetamide S-oxide by rat liver microsomes.大鼠肝脏微粒体对硫代乙酰胺和硫代乙酰胺S-氧化物的代谢

Drug Metab Dispos. 1978 Jul-Aug;6(4):379-88.

引用本文的文献

High activity of cytochrome P-450-linked aminopyrine N-demethylase in mouse brain microsomes, and associated sex-related difference.小鼠脑微粒体中细胞色素P-450相关氨基比林N-脱甲基酶的高活性及相关性别差异。

Biochem J. 1989 Aug 1;261(3):769-73. doi: 10.1042/bj2610769.

Induction of cytochrome P-450 isozymes upon repeated administration of nifedipine.多次服用硝苯地平后细胞色素P-450同工酶的诱导作用。

Eur J Drug Metab Pharmacokinet. 1991 Apr-Jun;16(2):103-6. doi: 10.1007/BF03189945.

Four forms of cytochrome P-450 in human fetal liver: purification and their capacity to activate promutagens.人类胎儿肝脏中的四种细胞色素P-450：纯化及其激活前诱变剂的能力。

Jpn J Cancer Res. 1991 Apr;82(4):426-32. doi: 10.1111/j.1349-7006.1991.tb01866.x.

Aminopyrine-N-demethylase. II. Characterization of a unique monooxygenase isoform P-450ap.氨基比林 -N-脱甲基酶。II. 独特的单加氧酶同工型P-450ap的特性

Eur J Drug Metab Pharmacokinet. 1991 Jul-Sep;16(3):213-7. doi: 10.1007/BF03189962.

Aminopyrine-N-demethylase. I. Directed modification of substrates' structure as a way of production of inducer of the monooxygenase isoform P-450b.氨基比林 -N-脱甲基酶。I. 作为生产单加氧酶同工型P - 450b诱导剂的一种方式对底物结构进行定向修饰。

Eur J Drug Metab Pharmacokinet. 1991 Jul-Sep;16(3):207-12. doi: 10.1007/BF03189961.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验