Reibson J D, Rosenberg G, Snyder A J, Cleary T J, Donachy J H, Felder G, Pierce W S
Department of Surgery, M. S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
ASAIO J. 1993 Jul-Sep;39(3):M415-8.
To eliminate the need for a separate parapleural compliance chamber, we are currently investigating the feasibility of an annular compliance chamber. This chamber wraps around the energy converter and fits between the blood pumps of the Pennsylvania State University electric total artificial heart. For the 100 cc total artificial heart, the compliance chamber volume is 76 ml and the tissue contacting surface area is approximately 85 cm2. The chamber is made of Dacron velour covered segmented polyether polyurethane urea. The annular compliance chamber was evaluated in vitro by comparing pump balance control performance against that obtained with an open vent. In the CVP range of 5-12 mmHg, LAP was maintained within 1 mmHg of the values obtained with a vent. Studies continue to determine the range of volumes over which the chamber is effective, differences in rates of diffusion, and performance during changes in barometric pressure.
为了无需单独的胸膜旁顺应性腔室，我们目前正在研究环形顺应性腔室的可行性。该腔室环绕能量转换器，并安装在宾夕法尼亚州立大学电动全人工心脏的血泵之间。对于100 cc的全人工心脏，顺应性腔室的容积为76 ml，组织接触表面积约为85 cm²。该腔室由覆盖有涤纶丝绒的分段聚醚聚氨酯脲制成。通过将泵平衡控制性能与开放通气口的性能进行比较，对环形顺应性腔室进行了体外评估。在中心静脉压5 - 12 mmHg的范围内，左心房压力维持在通气口所获值的1 mmHg以内。研究仍在继续，以确定该腔室有效的容积范围、扩散速率差异以及大气压力变化时的性能。
