Sueda T, Fukunaga S, Mitsui N, Matsuura Y
First Department of Surgery, Hiroshima University, School of Medicine, Japan.
ASAIO J. 1993 Jul-Sep;39(3):M725-8.
The authors devised an air lift pump oxygenator, comprised of double cylinders connected together and filled with perfluorocarbon (FC-75, 3M) as an oxygen carrier. While the oxygen enters the FC-75 through the lower inlet of one cylinder, the oxygenated FC-75 is lifted by an air lift pump and circulates in the two cylinders. FC-75 adds oxygen to the blood that infuses from the lower inlet of the other cylinder. The oxygenated blood is separated from the FC-75 by gravity and infused into the subject. The size of the cylinder is 2.2 cm in internal diameter and 17 cm in effective oxygenation height. The capacity of the oxygenator is 160 ml. PO2 went from 62 mmHg to 96 mmHg and PCO2 decreased from 31 mmHg to 25 mmHg at a blood flow of 50 ml/min and an oxygen flow of 2 L/min. Maximum blood flow was 60 ml/min and the blood reserve capacity was 20 ml/min. The air lift pump oxygenator has advantages, such as simple structure, no motor, and a small priming volume.
作者设计了一种气升泵式氧合器，它由连接在一起的双圆筒组成，并填充全氟碳化合物（FC - 75，3M公司生产）作为氧载体。当氧气通过一个圆筒的下部入口进入FC - 75时，充氧后的FC - 75由气升泵提升并在两个圆筒中循环。FC - 75向从另一个圆筒下部入口注入的血液中添加氧气。充氧后的血液通过重力与FC - 75分离并注入受试者体内。圆筒内径为2.2厘米，有效氧合高度为17厘米。氧合器容量为160毫升。在血流为50毫升/分钟、氧气流量为2升/分钟时，氧分压从62毫米汞柱升至96毫米汞柱，二氧化碳分压从31毫米汞柱降至25毫米汞柱。最大血流为60毫升/分钟，血液储备能力为20毫升/分钟。气升泵式氧合器具有结构简单、无电机、预充量小等优点。
