Blau J N
Lancet. 1978 Nov 25;2(8100):1136-9. doi: 10.1016/s0140-6736(78)92287-0.
The current view that the migraine aura arises from spasm of the major cerebral arteries and the ensuing headache from extracranial arterial vasodilatation is examined and refuted. It is proposed that the headache is due to stimulation of nociceptive nerve-endings in the walls of meningeal vessels (arterioles, venules, and particularly the dural venous sinuses); and that the aura arises from calibre changes in meningeal vessels that penetrate the outer cortex, resulting in localised inhibition or excitation. It is suggested that there are two types of migraine patients--vasodilators and vasoconstrictors.
当前认为偏头痛先兆源于大脑主要动脉痉挛，随后的头痛源于颅外动脉血管扩张的观点受到了审视并被驳斥。有人提出，头痛是由于刺激了脑膜血管（小动脉、小静脉，尤其是硬脑膜静脉窦）壁上的伤害性神经末梢；而先兆则源于穿透外层皮质的脑膜血管管径变化，导致局部抑制或兴奋。有人认为偏头痛患者有两种类型——血管扩张型和血管收缩型。
