Wang Wei, Zhu Chenlu, Martelletti Paolo
Headache Center, Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Department of Neurology, The First Affiliated Hospital of Shandong First Medical University, Jinan, China.
Pain Ther. 2024 Dec;13(6):1429-1445. doi: 10.1007/s40122-024-00668-5. Epub 2024 Oct 13.
In recent decades, cranial and cervical vascular disorders have become major global health concerns, significantly impacting patients, families, and societies. Headache is a prevalent symptom of these vascular diseases and can often be the initial, primary, or sole manifestation. The intricate relationship between headaches and cranial/cervical vascular disorders poses a diagnostic and therapeutic challenge, with the underlying mechanisms remaining largely elusive. Understanding this association is crucial for the early diagnosis, prevention, and intervention of such conditions. This review aims to provide a comprehensive overview of the clinical features and potential pathogenesis of headaches attributed to cranial and cervical vascular disorders and provide a reference for disease management and a basis for potential pathological mechanisms.
近几十年来，颅颈血管疾病已成为全球主要的健康问题，对患者、家庭和社会产生了重大影响。头痛是这些血管疾病的常见症状，通常可能是最初的、主要的或唯一的表现。头痛与颅/颈血管疾病之间的复杂关系带来了诊断和治疗挑战，其潜在机制在很大程度上仍不清楚。了解这种关联对于此类疾病的早期诊断、预防和干预至关重要。本综述旨在全面概述归因于颅颈血管疾病的头痛的临床特征和潜在发病机制，为疾病管理提供参考，并为潜在的病理机制提供依据。
