Janda J, Koutecký J, Lukes M, Lukesová M, Malis J
I. dĕtská klinika 2. LF UK, Praha-Motol.
Cesk Pediatr. 1993 Oct;48(10):577-80.
A single kidney in patients with agenesis or after nephrectomy is regarded as a risk factor. Primarily, the role of glomerular hyperfiltration and later possible glomerular sclerosis are emphasised. Complex treatment of Wilms tumour patients includes previous chemotherapy and radiotherapy. The aim of our study was to investigate late sequelae of this aggressive treatment on the morphology and function of a single kidney and to compare these results with a group of single kidney patients, where the diagnosis of Wilms tumour was excluded.
单肾在肾发育不全患者或肾切除术后患者中被视为一个风险因素。主要强调了肾小球高滤过的作用以及随后可能出现的肾小球硬化。肾母细胞瘤患者的综合治疗包括术前化疗和放疗。我们研究的目的是调查这种积极治疗对单肾形态和功能的晚期后遗症,并将这些结果与一组排除了肾母细胞瘤诊断的单肾患者进行比较。