Wang P W, Chen H Y, Li C H, Chen W J
Department of Nuclear Medicine, Chang Gung Memorial Hospital, Chang Gung Medical College, Kaohsiung, Taiwan, Republic of China.
Clin Nucl Med. 1993 Nov;18(11):964-6. doi: 10.1097/00003072-199311000-00008.
I-131 whole-body imaging may show characteristic findings in functioning, metastatic differentiated thyroid carcinoma. Nonthyroidal tumor uptake of I-131 is rare, but may mislead the physician to inappropriate treatment. A case is reported of a 59-year-old woman with papillary thyroid carcinoma who demonstrated strong uptake of I-131 in an abdominal cystic neurilemoma. Her serum thyroglobulin concentration at that time was low, at 3.35 ng/ml. Although the concentrating mechanism of I-131 was not clear, several clues pointed to the possibilities of nonthyroidal tumor uptake: 1) faster clearing of radioactivity than usual thyroid tissue, 2) persistent low serum thyroglobulin concentration, and 3) the presence of a cystic component in the nonthyroidal tumor.
I-131全身显像在功能性转移性分化型甲状腺癌中可能显示出特征性表现。I-131在非甲状腺肿瘤中的摄取很少见，但可能会误导医生进行不恰当的治疗。本文报道了一例59岁的乳头状甲状腺癌女性患者，其腹部囊性神经鞘瘤对I-131有强烈摄取。当时她的血清甲状腺球蛋白浓度较低，为3.35 ng/ml。虽然I-131的浓聚机制尚不清楚，但有几条线索提示非甲状腺肿瘤摄取的可能性：1）放射性清除比正常甲状腺组织更快；2）血清甲状腺球蛋白浓度持续偏低；3）非甲状腺肿瘤中存在囊性成分。
