Cerny V A
Psychopharmacology (Berl). 1976 Nov 24;50(3):269-74. doi: 10.1007/BF00426843.
Ovariectomized cats with intracerebral implants of reserpine, a monoamine depletor, were tested for sexual behavior by introducing them to sexually vigorous males and by artificial stimulation. Approximately a third of the animals mated in response to reserpine and another third exhibited some components of sexual behavior. The behavior exhibited by these animals had none of the frenzy of normal estrous behavior. Some components of the normal pattern were missing while all others were curtailed in duration and vigor. These animals responded with normal sexual behavior to intracerebrally and systemically administered estrogen. It is suggested that the unusual sexual behavior in response to reserpine was due to the release of these behavioral patterns from a monoamine system, inhibitory to sexual behavior.
给切除卵巢的猫脑内植入单胺耗竭剂利血平，通过将它们与性欲旺盛的雄性猫放在一起以及人工刺激来测试其性行为。大约三分之一的动物对利血平有交配反应，另外三分之一表现出一些性行为成分。这些动物表现出的行为没有正常发情行为的那种狂热。正常行为模式的一些成分缺失，而其他所有成分在持续时间和强度上都有所减弱。这些动物对脑内和全身给予的雌激素有正常的性行为反应。有人提出，对利血平出现的异常性行为是由于这些行为模式从抑制性行为的单胺系统中释放出来所致。
