Ure B M, Neugebauer E, Ullmann K, Driever R, Troidl H
Chirurgische Klinik, II. Lehrstuhls für Chirurgie, Universität Köln.
Chirurg. 1993 Oct;64(10):802-8.
Patient-controlled analgesia (PCA) is rarely used on surgical wards despite described advantages of this method as compared to conventional techniques. Uncertainties in patient selection and insufficient evaluation of this technique may explain these circumstances. The aim of our study was to evaluate PCA on general surgery and traumatology wards by means of standardized criteria for technology assessment (i.e. safety, practicability, benefit for patients and medical staff) and the efficacy of pain relief. In a prospective study we investigated 120 patients. In phase I, we performed analgesic therapy with tramadol/metamizol (50 ASA status I-IV patients). In phase II, piritramid had been applied to 70 ASA status I-II patients after an intermediate analysis of phase I. In 7% of the patients technical problems led to an early interruption even at the end of the study period. There were, however, no incidents which caused vital problems for the patients. A mean postoperative pain level of 55 visual analogue scale points (0-100 point scale) was achieved with tramadol/metamizol. PCA was stopped in 16% of the patients due to the occurrence of nausea or vomiting and in two patients due to insufficient pain relief. The use of piritramid in phase II led to lower pain levels and no interruptions of PCA because of ineffectivity or nausea/vomiting.(ABSTRACT TRUNCATED AT 250 WORDS)
尽管与传统技术相比,患者自控镇痛(PCA)具有诸多优势,但在外科病房中却很少使用。患者选择的不确定性以及对该技术评估不足可能是导致这种情况的原因。我们研究的目的是通过技术评估的标准化标准(即安全性、实用性、对患者和医务人员的益处)以及疼痛缓解的效果,来评估普通外科和创伤科病房中PCA的应用情况。在一项前瞻性研究中,我们调查了120名患者。在第一阶段,我们对50名ASA身体状况I - IV级的患者使用曲马多/安乃近来进行镇痛治疗。在第一阶段进行中期分析后,在第二阶段对70名ASA身体状况I - II级的患者使用了匹米诺定。在7%的患者中,即使在研究期末,技术问题也导致了早期中断。然而,没有发生对患者生命造成重大问题的事件。使用曲马多/安乃近后,患者术后平均疼痛水平为55分(视觉模拟量表,0 - 100分制)。16%的患者因出现恶心或呕吐而停止使用PCA,2名患者因镇痛效果不佳而停止使用。在第二阶段使用匹米诺定使疼痛水平降低,且没有因无效或恶心/呕吐而中断PCA的情况。(摘要截断于250字)