Yuan J M, Tang J, Hao H J
Department of Neurology, First Hospital, Beijing Medical University.
Zhonghua Nei Ke Za Zhi. 1993 Jun;32(6):375-7.
17 cases of Guillain-Barré syndrome (GBS) were admitted to The First Hospital of Beijing Medical University and Baoding Hospital from July, 1991 to October, 1992. Five patients had diarrhea before the onset of GBS and showed positive reaction for serum IgM antibodies to Campylobacter jejuni. They were considered to have Campylobacter jejuni enteritis as well. This incidence of Campylobacter jejuni enteritis in GBS patients was higher than in those with other neurological diseases and in normal controls. These five patients were all from countryside and had their onset in the summer and autumn. Moreover, four of them were below twenty-four years old. The epidemiological pattern was quite similar to that of Campylobacter jejuni enteritis in China. Our data showed the close association between GBS and Campylobacter jejuni enteritis and the possible mechanism was discussed.
1991年7月至1992年10月期间，17例格林-巴利综合征（GBS）患者入住北京医科大学第一医院和保定医院。5例患者在GBS发病前出现腹泻，空肠弯曲菌血清IgM抗体反应呈阳性。他们也被认为患有空肠弯曲菌肠炎。GBS患者中空肠弯曲菌肠炎的发病率高于其他神经系统疾病患者和正常对照组。这5例患者均来自农村，发病于夏秋季节。此外，其中4例年龄在24岁以下。这种流行病学模式与中国空肠弯曲菌肠炎的模式非常相似。我们的数据显示了GBS与空肠弯曲菌肠炎之间的密切关联，并对可能的机制进行了讨论。
