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通过血清学和培养检测吉兰-巴雷综合征患者空肠弯曲菌/结肠弯曲菌感染情况。

Detection of Campylobacter jejuni/C.coli infection in patients with Guillain-Barré syndrome by serology and culture.

作者信息

Hariharan H, Naseema K, Kumaran C, Shanmugam J, Nair M D, Radhakrishnan K

机构信息

Department of Pathology and Microbiology, University of Prince Edward Island, Charlottetown, Canada.

出版信息

New Microbiol. 1996 Jul;19(3):267-71.

PMID:8841044
Abstract

Serum samples from 43 cases of Guillain-Barré Syndrome (GBS), 32 non-GBS neurology patients, and 35 healthy persons from a medical institute in Kerala, India, were tested for antibody levels against a Campylobacter jejuni strain Penner serotype 0:19 by agglutination and ELISA. Twenty-six percent of samples from GBS cases showed high antibody levels in all assays. Of 8 stool samples of new GBS cases examined by culture, 38% were positive for C. jejuni/C. col1. The results suggest that at least a quarter of GBS cases studied were associated with Campylobacter infection.

摘要

对来自印度喀拉拉邦一家医疗机构的43例格林-巴利综合征(GBS)患者、32例非GBS神经科患者和35名健康人的血清样本,通过凝集试验和酶联免疫吸附测定(ELISA)检测了针对空肠弯曲菌Penner血清型0:19菌株的抗体水平。GBS病例样本中有26%在所有检测中显示出高抗体水平。在通过培养检查的8例新GBS病例的粪便样本中,38%的样本空肠弯曲菌/结肠弯曲菌呈阳性。结果表明,所研究的GBS病例中至少四分之一与弯曲菌感染有关。

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引用本文的文献

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Guillain Barré syndrome.吉兰-巴雷综合征
Mol Pathol. 2001 Dec;54(6):381-5.
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Campylobacter Enteritis and the Guillain-Barré Syndrome.空肠弯曲菌肠炎与格林-巴利综合征
Curr Infect Dis Rep. 2001 Apr;3(2):116-122. doi: 10.1007/s11908-996-0033-5.