Zimmermann R
Department für Frauenheilkunde, Universität Zürich.
Geburtshilfe Frauenheilkd. 1993 Oct;53(10):677-80. doi: 10.1055/s-2007-1023607.
A review of the effectiveness of antenatal screening for syphilis in the 3 year period 1989 to 1991 was made at the Department of Obstetrics, University of Zurich. In a total of 5640 pregnancies, 30 had a reactive TPHA-result. Using FTA-ABS-test and IgM-tests, 2 were false positive and 27 were considered as seropositive without signs of infection. Only one patient had a serology consistent with a latent syphilis. In Switzerland, every year approx. 9 newborns with positive serology for syphilis are found. Most of them, however, are not infected and the result only reflects the serostatus of the mother. Because of these poor results we doubt the usefulness of an antenatal screening programme for syphilis.
苏黎世大学妇产科对1989年至1991年这3年期间梅毒产前筛查的有效性进行了回顾。在总共5640例妊娠中，有30例梅毒螺旋体血细胞凝集试验（TPHA）结果呈阳性。采用荧光密螺旋体抗体吸收试验（FTA - ABS试验）和IgM试验，其中2例为假阳性，27例被认为血清学阳性但无感染迹象。只有1例患者的血清学结果符合潜伏梅毒。在瑞士，每年大约会发现9例梅毒血清学阳性的新生儿。然而，他们中的大多数并未感染，检测结果仅反映了母亲的血清状态。鉴于这些不佳的结果，我们对梅毒产前筛查项目的实用性表示怀疑。
