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噻唑卤制菌素，一种由马杜拉放线菌产生的新型细胞保护物质。II. 物理化学性质及结构测定。

Thiazohalostatin, a new cytoprotective substance produced by Actinomadura. II. Physico-chemical properties and structure determination.

作者信息

Shindo K, Yamagishi Y, Kawai H

机构信息

Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.

出版信息

J Antibiot (Tokyo). 1993 Nov;46(11):1638-42. doi: 10.7164/antibiotics.46.1638.

DOI:10.7164/antibiotics.46.1638
PMID:8270484
Abstract

Thiazohalostatin is a new cytoprotective substance produced by Actinomadura sp. HQ24. Its structure was elucidated as shown in Fig. 1 by NMR spectral analyses and chemical modifications. Thiazohalostatin was found to possess a novel skeleton containing trichloropyrrole and thiazoline ring moieties.

摘要

噻唑卤制菌素是由马杜拉放线菌HQ24产生的一种新型细胞保护物质。通过核磁共振光谱分析和化学修饰，其结构如图1所示得以阐明。发现噻唑卤制菌素具有一个包含三氯吡咯和噻唑啉环部分的新型骨架。

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