Shroff H J, Dashatwar D R, Deshpande R P, Waigmann H R
Department of Dermatology & STD, Grant Medical College, Bombay.
J Assoc Physicians India. 1993 Apr;41(4):241-2.
We report the first case of AIDS-associated Kaposi's Sarcoma in a 35 year old Indian female, a commercial sex worker, with lesions involving skin and mucous membranes. Diagnosis was confirmed on histopathology, electron microscopy, seropositivity, (ELISA and Western Blot) as well as Pepti-LAV test and viral culture. Antibodies to human immunodeficiency virus, both HIV-1 & 2, were present. HLA DR5,7 was positive on oligotyping. Genetic predisposition, therefore, may be suspected.
我们报告了首例艾滋病相关卡波西肉瘤病例,患者为一名35岁的印度女性商业性工作者,病变累及皮肤和黏膜。通过组织病理学、电子显微镜检查、血清学阳性(酶联免疫吸附测定和免疫印迹法)以及肽 - LAV检测和病毒培养确诊。同时检测到针对人类免疫缺陷病毒1型和2型的抗体。寡核苷酸分型显示HLA DR5、7呈阳性。因此,可能存在遗传易感性。