Byrd R P, Byrd R P, Roy T M
Division of Respiratory Medicine, University of Louisville School of Medicine, KY.
J Ky Med Assoc. 1993 Nov;91(11):501-3.
Human chorionic gonadotropin (HCG) is typically associated with pregnancy or germ cell tumors. Although it may be detected within the tissue of a variety of malignant tumors by immunohistochemical methods, including primary lung cancers, serum levels are rarely elevated in non-germ cell malignancies. We describe a young lady who presented with chest discomfort and dyspnea. Clinically, she was thought to have deep venous thrombosis. She presumed that she was pregnant since her last menses was 3 months before admission. She also had breast tenderness similar to that which she had experienced during a previous pregnancy. A serum value for B-HCG suggested that she was 4 to 6 weeks pregnant. Further investigation confirmed that this patient was not pregnant, but had developed a gonadotropin secreting adenocarcinoma of the lung.
人绒毛膜促性腺激素（HCG）通常与妊娠或生殖细胞肿瘤相关。尽管通过免疫组化方法在包括原发性肺癌在内的多种恶性肿瘤组织中可能检测到它，但在非生殖细胞恶性肿瘤中血清水平很少升高。我们描述一位出现胸部不适和呼吸困难的年轻女性。临床上，她被认为患有深静脉血栓形成。她推测自己怀孕了，因为她上次月经是在入院前3个月。她还出现了与前次妊娠时相似的乳房压痛。β-HCG血清值提示她怀孕4至6周。进一步检查证实该患者并未怀孕，而是患了分泌促性腺激素的肺腺癌。
