Krauer P, Maire R, Hofer H O, Flury R, Vetter W, Greminger P
Departement für Innere Medizin, Universitätsspital Zürich.
Schweiz Rundsch Med Prax. 1993 Dec 7;82(49):1413-9.
Early diagnosis of hemochromatosis may prevent the numerous risks of iron overload. One of the most common early manifestations of this disease is arthropathy. The clinical and radiologic findings of hemochromatosis arthropathy are discussed. Diagnosis is suggested by simple laboratory tests and confirmed by liver biopsy with measurement of hepatic iron content. Treatment includes the removal of the excess body iron by phlebotomy. Unfortunately, symptoms of arthropathy tend to be resistant to phlebotomy.
血色素沉着症的早期诊断可预防铁过载带来的诸多风险。这种疾病最常见的早期表现之一是关节病。本文讨论了血色素沉着症关节病的临床和放射学表现。通过简单的实验室检查可提示诊断,并通过肝活检测量肝铁含量来确诊。治疗包括通过放血去除体内多余的铁。不幸的是,关节病症状往往对放血治疗有抵抗性。