Bulajic-Kopjar M, Magnus P, Lie R T
Avdeling for Samfunnsmedisin, Statens Institutt for Folkehelse, Oslo.
Tidsskr Nor Laegeforen. 1993 Oct 20;113(25):3126-8.
The occurrence of anencephalus as reported to the Norwegian Medical Birth Registry has fallen from 4.9 per 10,000 births in 1967-71 to 2.7 in 1987-90. The decrease is particularly noticeable for births with a gestational length of 28 weeks or more. On the other hand, there has been a significant increase in the number of cases of anencephalus with a gestational age less than 28 weeks. The occurrence of meningomyelocele has remained relatively stable throughout the same period. Ascertainment error could explain these contrasting trends, since cases of anencephalus detected on ultrasound screening may lead to early termination of pregnancy without notification to the Medical Birth Registry. Better routines for notification of malformations are needed to improve the basis for surveillance in Norway.
据挪威医学出生登记处报告，无脑儿的发生率已从1967 - 1971年的每10000例出生4.9例降至1987 - 1990年的2.7例。这种下降在妊娠28周或更长时间的分娩中尤为明显。另一方面，孕周小于28周的无脑儿病例数量显著增加。在同一时期，脊髓脊膜膨出的发生率一直相对稳定。确诊误差可能解释了这些相反的趋势，因为超声筛查发现的无脑儿病例可能导致早期终止妊娠，而未通知医学出生登记处。挪威需要更好的畸形报告程序来改善监测基础。
