Høst A H, Duus T, Ibsen T B, Høst A
Skolelaegen, Nordborg Kommune, Sønderborg Sygehus, børneafdelingen.
Ugeskr Laeger. 1993 Dec 6;155(49):3978-81.
A cross sectional study of 1064 unselected school children aged 6-17 years obtained the following for 851 of them (80%): complete data from a questionnaire on current asthma diagnosed by a physician, information on previous recurrent wheezing and present exposure to tobacco smoking combined with measurement of peak expiratory flow rate (PEFR) before and after six minutes running. Seventy-five (8.8%) had had previous periods of recurrent wheezing, and 535 (62.7%) were exposed to tobacco smoking at home. A correlation was found between passive smoking and previous recurrent wheezing. Thirty-four (4.0%) suffered from current asthma. Thirty-one children (3.6%) without an earlier diagnosis of asthma showed a significant exercise-induced fall in PEFR) (at least 15%). Thirty of these 31 children were followed up, and at reinvestigation, 27 (95%) were confirmed to suffer from hyperreactive airways based on significant exercise-induced fall in PEFR and/or a significantly increased variability of PEFR of at least 15% as measured by home recordings of PEFR. In conclusion the point prevalence of asthma diagnosed by a physician was 4.0%. In addition at least 3.2% had reproducible significant bronchial hyperreactivity indicating a point prevalence of asthma/clinically significant bronchial hyperreactivity of at least 7.2%. Asthma seems to be underdiagnosed in school children. Furthermore, our results indicate an association between passive smoking and recurrent wheezing.
一项针对1064名6至17岁未经过筛选的在校儿童的横断面研究,对其中851名儿童(80%)获取了以下信息:一份关于由医生诊断的当前哮喘的问卷的完整数据、既往反复喘息的信息、当前接触吸烟的情况,以及六分钟跑步前后的呼气峰值流速(PEFR)测量值。75名儿童(8.8%)有过既往反复喘息期,535名儿童(62.7%)在家中接触吸烟。发现被动吸烟与既往反复喘息之间存在相关性。34名儿童(4.0%)患有当前哮喘。31名先前未被诊断为哮喘的儿童表现出运动诱发的PEFR显著下降(至少15%)。对这31名儿童中的30名进行了随访,再次调查时,根据运动诱发的PEFR显著下降和/或通过家庭PEFR记录测量的PEFR变异性显著增加至少15%,27名(95%)被确诊患有气道高反应性。总之,医生诊断的哮喘现患率为4.0%。此外,至少3.2%有可重复的显著支气管高反应性,表明哮喘/具有临床意义的支气管高反应性的现患率至少为7.2%。哮喘在学龄儿童中似乎诊断不足。此外,我们的结果表明被动吸烟与反复喘息之间存在关联。