骨髓病变的磁共振成像：在T1加权、脂肪抑制T2加权和短TI反转恢复（STIR）图像上的相对显见度。

MR imaging of bone marrow lesions: relative conspicuousness on T1-weighted, fat-suppressed T2-weighted, and STIR images.

作者信息

Mirowitz S A, Apicella P, Reinus W R, Hammerman A M

机构信息

Mallinckrodt Institute of Radiology, Jewish Hospital of St. Louis, Washington University School of Medicine, MO 63110.

出版信息

AJR Am J Roentgenol. 1994 Jan;162(1):215-21. doi: 10.2214/ajr.162.1.8273669.

DOI:10.2214/ajr.162.1.8273669

PMID:8273669

Abstract

OBJECTIVE

Fat-saturation pulse sequences offer important potential advantages for depiction of bone marrow lesions on MR images. The objectives of this study were to evaluate the relative conspicuousness of bone marrow lesions on images obtained by using two of the most widely available fat-suppression techniques, short-TI inversion recovery (STIR) and fat-saturation T2-weighted imaging, and to analyze the effect of these methods on image quality. In addition, we sought to determine if either or both of these sequences provide significant advantages relative to conventional T1-weighted spin-echo images for the evaluation of bone marrow lesions.

SUBJECTS AND METHODS

T1-weighted (600/15 [TR/TE]), STIR (2500/20/160 [TR/TE/TI]), and fat-saturation T2-weighted (2500/20-70) MR images were obtained with a 1.5-T system in 34 consecutive patients with suspected bone marrow lesions. The conspicuousness of 36 lesions was evaluated subjectively by three radiologists, who also evaluated the MR images for how well they showed margination and extent of the lesion, image uniformity, motion artifacts, and overall image quality. In addition, lesion contrast on these sequences was compared quantitatively by using percentage contrast measurements.

RESULTS

Lesions were qualitatively equally conspicuous with all four pulse sequences. Quantitative measurements indicated that lesions were more conspicuous on fat-saturation T2-weighted and STIR images than on T1-weighted images (p < .001). Differences between the first two sequences were not significant. Factors related to image quality, including reduction in motion artifacts and image uniformity, were generally superior on T1-weighted images.

CONCLUSION

T1-weighted, fat-saturation T2-weighted, and STIR sequences all provide a high degree of sensitivity for depiction of most types of bone marrow abnormalities. Although the conspicuousness of lesions is similar on fat-saturation T2-weighted and STIR images, the former sequence has several practical advantages, including acquisition of more slices per unit time and improved tissue specificity. The combination of T1-weighted and either fat-saturation T2-weighted or STIR images is highly effective for the evaluation of bone marrow lesions.

摘要

目的

脂肪饱和脉冲序列在磁共振成像（MRI）上显示骨髓病变方面具有重要的潜在优势。本研究的目的是评估使用两种最常用的脂肪抑制技术（短TI反转恢复序列（STIR）和脂肪饱和T2加权成像）所获得图像上骨髓病变的相对明显程度，并分析这些方法对图像质量的影响。此外，我们试图确定这两种序列中的任何一种或两种相对于传统T1加权自旋回波图像在评估骨髓病变方面是否具有显著优势。

受试者与方法

使用1.5T系统对34例连续的疑似骨髓病变患者进行T1加权（600/15 [TR/TE]）、STIR（2500/20/160 [TR/TE/TI]）和脂肪饱和T2加权（2500/20 - 70）MRI检查。由三位放射科医生主观评估36个病变的明显程度，他们还评估了MRI图像在显示病变边界和范围、图像均匀性、运动伪影以及整体图像质量方面的表现。此外，通过使用百分比对比度测量对这些序列上的病变对比度进行定量比较。