Huang Xianming, Cai Chenhui, Huang Song, Tang Chao, Zhao Xu, Wen Xuan, Zhang Ying, Chu Tongwei
Department of Orthopedic Surgery, Second Affiliated Hospital of Army (Third) Military Medical University, Chongqing, China.
Department of Orthopaedic Surgery, Dazhou Central Hospital, Dazhou, China.
Global Spine J. 2025 May 9:21925682251339995. doi: 10.1177/21925682251339995.
Study DesignA case-controlled retrospective study.ObjectiveWe aimed to explore the effectiveness of MRI-based VBQ scores derived by different MRI sequences in assessing risk of an osteoporotic vertebral compression fracture (OVCF) in age- and sex-controlled patients.MethodsThis retrospective study included patients hospitalized for OVCF (fracture group) and degenerative lumbar disease (non-fracture group) from July 2022 to July 2024. Patients in both groups were matched for sex and age in a 1:1 ratio. VBQ scores were acquired from non-contrast lumbosacral MRI T1-weighted, T2-weighted, and short tau inversion recovery (STIR)-weighted sequences. A receiver operating characteristic (ROC) curve and area under the ROC (AUC) were plotted to evaluate the diagnostic accuracy.ResultsA total of 168 patients (n = 84 in each group) were included. VBQ-T1 scores were higher in the fracture group (4.4 vs 4.1, = 0.001), with an AUC of 0.641 to predict OVCF. VBQ-T2 scores were higher in the fracture group (0.60 vs 0.55, < 0.001), with an AUC of 0.697. Additionally, VBQ-T2-STIR scores were higher in the fracture group (0.99 vs 0.83, = 0.004), with an AUC of 0.644. Multivariate logistic regression analysis identified VBQ-T2, rather than VBQ-T1 or VBQ-T2-STIR, as an independent risk factor for OVFC.ConclusionThis study evaluated the MRI-based VBQ scores in assessing risk of OVCF based on age- and sex-matched cases. The VBQ-T2 score appears most promising for evaluating the risk of OVCF in clinical practice.
研究设计
一项病例对照回顾性研究。
目的
我们旨在探讨不同MRI序列得出的基于MRI的VBQ评分在评估年龄和性别匹配患者骨质疏松性椎体压缩骨折（OVCF）风险方面的有效性。
方法
这项回顾性研究纳入了2022年7月至2024年7月因OVCF住院的患者（骨折组）和退行性腰椎疾病患者（非骨折组）。两组患者按1:1的比例进行性别和年龄匹配。从非增强腰骶部MRI的T1加权、T2加权和短tau反转恢复（STIR）加权序列中获取VBQ评分。绘制受试者操作特征（ROC）曲线和ROC曲线下面积（AUC）以评估诊断准确性。
结果
共纳入168例患者（每组n = 84）。骨折组的VBQ-T1评分更高（4.4对4.1，P = 0.001），预测OVCF的AUC为0.641。骨折组的VBQ-T2评分更高（0.60对0.55，P < 0.001），AUC为0.697。此外，骨折组的VBQ-T2-STIR评分更高（0.99对0.83，P = 0.004），AUC为0.644。多因素逻辑回归分析确定VBQ-T2而非VBQ-T1或VBQ-T2-STIR是OVFC的独立危险因素。
结论
本研究基于年龄和性别匹配的病例评估了基于MRI的VBQ评分在评估OVCF风险方面的情况。VBQ-T2评分在临床实践中评估OVCF风险方面似乎最有前景。
