Pui M H, Chang S K
Department of Radiology, National University Hospital, Singapore.
Skeletal Radiol. 1996 Feb;25(2):149-52. doi: 10.1007/s002560050052.
To prospectively compare inversion recovery (IR) fast spin-echo (FSE) with T1-weighted spin-echo (SE) and T2-weighted chemical-shift fat-saturated (FS) FSE magnetic resonance sequences in the detection of bone marrow abnormality.
Twenty-nine sets of T1-weighted SE [400-640/10-20 (TR/TE)], T2-weighted FS-FSE [2400-3800/91-112/8 (TR/TE/ETL), and IR-FSE [3700-6000/12-14/170/8 (TR/TE/T1/ETL)] images were acquired with a 1.5-T magnet in 27 patients with bone marrow lesions. The visibility, margination, and extent of 41 lesions, image quality, contrast, and artifacts were qualitatively and quantitatively compared.
The lesions were more conspicuous on the IR-FSE than on the T1-weighted SE and T2-weighed FS-FSE images. The extent of lesions was similar for all three sequences. Image quality was better and there were fewer motion artifacts on the T1-weighted images. The mean lesion contrasted-to-noise ratio was significantly higher on the T1-weighted images (p < 0.05).
The IR-FSE sequence is highly sensitive for detecting bone marrow pathology, with scan time comparable to the T1-weighted SE and T2-weighted FS-FSE sequences.
前瞻性比较反转恢复（IR）快速自旋回波（FSE）序列与T1加权自旋回波（SE）序列以及T2加权化学位移脂肪抑制（FS）FSE磁共振序列在检测骨髓异常方面的效果。
使用1.5-T磁体对27例患有骨髓病变的患者采集了29组T1加权SE序列[400 - 640/10 - 20（TR/TE）]、T2加权FS - FSE序列[2400 - 3800/91 - 112/8（TR/TE/ETL）]以及IR - FSE序列[3700 - 6000/12 - 14/170/8（TR/TE/T1/ETL）]的图像。对41处病变的可见性、边界清晰度和范围、图像质量、对比度及伪影进行了定性和定量比较。
病变在IR - FSE序列图像上比在T1加权SE序列和T2加权FS - FSE序列图像上更明显。所有三个序列显示的病变范围相似。T1加权图像的图像质量更好且运动伪影更少。T1加权图像上病变的平均对比噪声比显著更高（p < 0.05）。
IR - FSE序列在检测骨髓病变方面高度敏感，其扫描时间与T1加权SE序列和T2加权FS - FSE序列相当。
