控制噬菌体Mu裂解发育的蛋白质-DNA组装体

Protein-DNA assemblies controlling lytic development of bacteriophage Mu.

作者信息

Baker T A

机构信息

Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

出版信息

Curr Opin Genet Dev. 1993 Oct;3(5):708-12. doi: 10.1016/s0959-437x(05)80087-5.

DOI:10.1016/s0959-437x(05)80087-5

PMID:8274852

Abstract

Recent analysis of the mechanism and regulation of transposition by bacteriophage Mu has emphasized the importance of controlled assembly of specific protein-DNA complexes. Both the Mu transposase and the Mu repressor engage in multiple protein-protein and protein-DNA interactions that modulate the outcome of a phage infection.

摘要

最近对噬菌体Mu转座机制和调控的分析强调了特定蛋白质-DNA复合物可控组装的重要性。Mu转座酶和Mu阻遏物都参与多种蛋白质-蛋白质和蛋白质-DNA相互作用，这些相互作用调节噬菌体感染的结果。