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在应用脂微球前列地尔E1治疗膈疝期间动脉导管瘤样扩张。

Aneurysmal dilatation of ductus arteriosus during lipo-prostaglandin E1 therapy for diaphragmatic hernia.

作者信息

Tohyama M, Baba A, Tsuno T, Aonuma K, Komiyama A

机构信息

Department of Paediatrics, Shinshu University, Matsumoto, Japan.

出版信息

Eur J Pediatr. 1993 Nov;152(11):877-9. doi: 10.1007/BF01957520.

Abstract

We report a case of congenital diaphragmatic hernia in which aneurysmal dilatation of ductus arteriosus developed after lipo-prostaglandin E1 (PGE1) therapy for persistent fetal circulation. After surgery Lipo-PGE1 was used at a dosage of 5 ng/kg per minute from days 2-9 during which aneurysmal dilatation (7 mm in diameter) developed and remained thereafter. Ductus arteriosus ligation was then performed. Lipo-PGE1 may promote ductus arteriosus dilatation in cases of persistent fetal circulation.

摘要

我们报告了一例先天性膈疝病例,该病例在使用脂微球前列腺素E1(PGE1)治疗持续性胎儿循环后出现动脉导管瘤样扩张。术后,从第2天至第9天以每分钟5 ng/kg的剂量使用脂微球PGE1,在此期间出现了动脉导管瘤样扩张(直径7 mm),之后持续存在。随后进行了动脉导管结扎术。脂微球PGE1在持续性胎儿循环病例中可能会促进动脉导管扩张。

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