The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.
作者信息
Gearing D P, Druck T, Huebner K, Overhauser J, Gilbert D J, Copeland N G, Jenkins N A
机构信息
Immunex Research and Development Corporation, Seattle, Washington 98101.
出版信息
Genomics. 1993 Oct;18(1):148-50. doi: 10.1006/geno.1993.1441.
PMID:8276403
Abstract
The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.
摘要
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