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The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.

作者信息

Gearing D P, Druck T, Huebner K, Overhauser J, Gilbert D J, Copeland N G, Jenkins N A

机构信息

Immunex Research and Development Corporation, Seattle, Washington 98101.

出版信息

Genomics. 1993 Oct;18(1):148-50. doi: 10.1006/geno.1993.1441.

DOI:10.1006/geno.1993.1441
PMID:8276403
Abstract

The leukemia inhibitory factor receptor (LIFR) gene was localized to human chromosome 5p12-p13 by somatic cell hybrid analysis. Interspecific backcross analysis revealed that the murine locus was on chromosome 15 in a region of homology with human chromosome 5p. In both human and mouse genomes, the LIFR locus was linked to the genes encoding the receptors for interleukin-7, prolactin, and growth hormone.

摘要

相似文献

1
The leukemia inhibitory factor receptor (LIFR) gene is located within a cluster of cytokine receptor loci on mouse chromosome 15 and human chromosome 5p12-p13.
Genomics. 1993 Oct;18(1):148-50. doi: 10.1006/geno.1993.1441.
2
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