Explaining attitudes toward medication compliance among a seriously mentally ill population.

Data from a clinical trial of consumer-delivered case management services were used to construct an explanatory model for attitudes toward medication compliance, focusing on psychosocial factors. A regression model explaining attitudes toward medication compliance shows that more positive attitudes toward compliance are related to older age, fewer symptoms, and a broader array of daily activities involving social relations. Participation in social activities is a practical goal of psychosocial rehabilitation services that support compliance with medication regimens and psychiatric treatment.