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对精神科药物治疗的态度:治疗体验

Attitudes toward psychiatric drug treatment: the experience of being treated.

作者信息

De Las Cuevas Carlos, Sanz Emilio J

机构信息

Department of Psychiatry, School of Medicine, University of La Laguna, Campus de Ofra, Carretera La Cuesta-Taco s/n., 38071, La Laguna Tenerife, Canary Islands, Spain.

出版信息

Eur J Clin Pharmacol. 2007 Nov;63(11):1063-7. doi: 10.1007/s00228-007-0358-5. Epub 2007 Aug 16.

Abstract

BACKGROUND

Effectiveness and tolerability of psychiatric medications are not only determined by the drug's pharmacological profile but through the interaction of different factors, including patients' attitudes toward their prescribed medications. Increased knowledge about those attitudes may help prescribers to improve patient concordance and thereby the effectiveness of the pharmacological therapy.

OBJECTIVE

The goal of this study was to assess stable psychiatric outpatients' attitudes toward psychiatric drug treatment and to what extent patients and public opinions on this subject diverge as a consequence of being on this type of medication.

METHODS

Two anonymous self-reported questionnaires [Drug Attitude Inventory (DAI)-10 and an abridge version of Beliefs about Medicines Questionnaire (BMQ)] were administered to 270 stable psychiatric outpatients under treatment and 292 citizens naïve to psychotropic medication.

RESULTS

Psychiatric patients showed a more positive attitude toward medication (DAI score 3.6 vs. -0.7; range -10 to +10; negative to positive). Up to 77% of patients showed positive scores compared with only 36% in the general population. Multiple regression analysis showed that none of the variables in the analysis have a predictive value with regard to the attitude toward psychiatric drugs used.

CONCLUSION

The continuous use of psychotropic medication shapes the opinion of the users toward a more beneficial perception of medications, but the opinion on the general population, where stigmatizing attitudes are born, is more negative toward them. For psychiatrists and their patients, trying to achieve a better understanding of each other's expectations and reaching concordance is mandatory.

摘要

背景

精神科药物的有效性和耐受性不仅取决于药物的药理学特性,还受到不同因素的相互作用影响,包括患者对所开药物的态度。对这些态度的了解增加可能有助于开处方者提高患者的依从性,从而提高药物治疗的有效性。

目的

本研究的目的是评估稳定的精神科门诊患者对精神科药物治疗的态度,以及患者和公众对该主题的看法因使用此类药物而产生的差异程度。

方法

对270名正在接受治疗的稳定精神科门诊患者和292名未使用过精神药物的市民进行了两份匿名的自我报告问卷[药物态度量表(DAI)-10和药物信念问卷(BMQ)的简化版]调查。

结果

精神科患者对药物表现出更积极的态度(DAI评分3.6对-0.7;范围-10至+10;从消极到积极)。高达77%的患者得分呈阳性,而普通人群中只有36%。多元回归分析表明,分析中的变量均对所使用的精神科药物的态度没有预测价值。

结论

精神药物的持续使用使使用者对药物的看法更倾向于有益,但在存在污名化态度的普通人群中,对精神药物的看法更消极。对于精神科医生及其患者来说,努力更好地理解彼此的期望并达成共识是必不可少的。

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