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经阴道超声诊断为多囊卵巢的女性的血浆雄激素和性激素结合球蛋白

Plasma androgens and sex hormone binding globulin in women with polycystic ovaries diagnosed by transvaginal ultrasound.

作者信息

Yoshino K, Takahashi K, Eda Y, Okada S, Kitao M

机构信息

Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.

出版信息

J Reprod Med. 1993 Nov;38(11):858-62.

PMID:8277481
Abstract

In order to investigate the androgen and sex hormone binding globulin (SHBG) levels in the polycystic ovary, we compared the total testosterone, free testosterone and SHBG levels in three patterns of polycystic ovary diagnosed with transvaginal ultrasonography (18 in group 1, fewer than 5 cysts identified; 16 in group 2, 5-10 cysts; and 27 in group 3, 10 or more). Free testosterone, but not total testosterone, significantly correlated with body mass index. Androgen levels were found to increase and SHBG levels to decrease with increases in the amount of ovarian cysts, and the evaluation of free testosterone was important in diagnosing the polycystic ovary syndrome.

摘要

为了研究多囊卵巢中的雄激素和性激素结合球蛋白(SHBG)水平,我们比较了经阴道超声诊断的三种多囊卵巢模式下的总睾酮、游离睾酮和SHBG水平(第1组18例,发现囊肿少于5个;第2组16例,5 - 10个囊肿;第3组27例,10个或更多)。游离睾酮而非总睾酮与体重指数显著相关。随着卵巢囊肿数量的增加,雄激素水平升高而SHBG水平降低,游离睾酮的评估对多囊卵巢综合征的诊断很重要。

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[Changes in serum androgen levels in patients with polycystic ovary syndrome].
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