曲酸对黄曲霉Link分离株产黄曲霉毒素的刺激作用。

The stimulatory effect of kojic acid on the production of aflatoxin by isolates of Aspergillus flavus Link.

作者信息

El-Khadem M, Tewfik M S, Hamdi Y A

出版信息

Zentralbl Bakteriol Parasitenkd Infektionskr Hyg. 1976;131(3):497-500. doi: 10.1016/s0044-4057(76)80037-8.

Abstract

Kojic acid at the levels of 0.01, 0.1, and 1.0% (w/v) was incorporated in the growth media of Aspergillus flavus. In the presence of 0.01% of kojic acid, isolates I, II, and III produced 157, 113, and 135% aflatoxin, respectively, as compared to the control. At the highest level of kojic acid, i.e. 1%, aflatoxin production was inhibited to 74% in isolate I, but was little affected in isolate II (104%) and strongly inhibited in isolate III (54%). Kojic acid, at a concentration of 0.1%, was still stimulatory to isolate II, while it was inhibitory to isolates I and III. The dry weight of mycelia of the three isolates was not affected by kojic acid addition.

摘要

将浓度为0.01%、0.1%和1.0%（w/v）的曲酸添加到黄曲霉的生长培养基中。在含有0.01%曲酸的情况下，与对照相比，分离株I、II和III分别产生了157%、113%和135%的黄曲霉毒素。在曲酸的最高浓度即1%时，分离株I的黄曲霉毒素产量被抑制至74%，但分离株II受影响较小（104%），而分离株III受到强烈抑制（54%）。浓度为0.1%的曲酸对分离株II仍有刺激作用，而对分离株I和III有抑制作用。添加曲酸对这三种分离株的菌丝体干重没有影响。