Janovská D, Burian V, Kuzemenská P
Zentralbl Bakteriol Orig A. 1976 Nov;236(2-3):224-30.
During the period 1970-1973 (1st half), 281 strains of Neisseria meningitidis from carriers and 35 from patients were tested for their sensitivity to a wide spectrum of chemotherapeutics. From the results of the tests for sensitivity in vitro, the conclusion is drawn that ampicillin, carbenicillin, and rifamycin SV may be considered as having a good action upon Neisseria meningitidis. The preparations of intermediate efficacy include penicillin, cephaloridine, chloramphenicol, and tetracyclin. As to sulphonamides, the presence of resistant strains was established. This phenomenon was rare when sulphonamide had been combined with trimetoprim.
在1970年至1973年上半年期间,对281株来自带菌者的脑膜炎奈瑟菌和35株来自患者的脑膜炎奈瑟菌进行了多种化疗药物的敏感性测试。根据体外敏感性测试结果得出结论,氨苄西林、羧苄西林和利福霉素SV对脑膜炎奈瑟菌可能具有良好的作用。中等疗效的制剂包括青霉素、头孢噻啶、氯霉素和四环素。至于磺胺类药物,已发现有耐药菌株存在。当磺胺类药物与甲氧苄啶合用时,这种现象很少见。