脑膜炎奈瑟菌菌株对抗菌药物的敏感性试验。
Sensitivity test on Neisseria meningitidis strains to antimicrobial drugs.
作者信息
Voros S, Sackey J Q, Salles C A, Marbell E C, Grant F C, Nimo P K, Belcher D W, Chew G, Adibo M E
出版信息
Ghana Med J. 1975 Sep;14(3):188-92.
PMID:826042
Abstract
- The Authors present the antibiotic sensitivity pattern of 62 Neisseria meningitidis strains isolated in Northern Ghana (Bawku, Navrongo, Bolgatanga and Nalerigu) in February-March, 1973. The following antibiotics or chemotherapeutic drugs were effective in vitro: Penicillin 100%, Ampicillin 100%, Chloramphenicol 100%, Tetracycline 100%, Erythromycin 100% (Nalidixic acid 100%, Nitrofurantion 100%), and the following were less effective: Streptomycin 61.2%, Novobiocin 100% (weakly sensitive), Oleandomycin 95.1% (weakly sensitive), Septrin 87%, Sulphafurazole 91.9%, Sulphadiazine 91.9%. All the isolates were Colistin resistant. 2. The sex and age distribution of patients with positive culture for Neisseria meningitidis shows the preponderance of males over females and the dominance of the group of 5-15 years of age over the other age groups. These results are in good agreement with previous data collected in other countries of the "meningitis belt".
摘要
- 作者展示了1973年2月至3月在加纳北部（巴库、纳瓦龙戈、博尔加坦加和纳莱古）分离出的62株脑膜炎奈瑟菌的抗生素敏感性模式。以下抗生素或化疗药物在体外有效：青霉素100%、氨苄青霉素100%、氯霉素100%、四环素100%、红霉素100%（萘啶酸100%、呋喃妥因100%），而以下药物效果较差：链霉素61.2%、新生霉素100%（轻度敏感）、竹桃霉素95.1%（轻度敏感）、复方新诺明87%、磺胺异恶唑91.9%、磺胺嘧啶91.9%。所有分离株对多粘菌素耐药。2. 脑膜炎奈瑟菌培养阳性患者的性别和年龄分布显示，男性多于女性，5至15岁年龄组占主导地位，高于其他年龄组。这些结果与在“脑膜炎带”其他国家收集的先前数据高度一致。
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