Friedenreich C M
Department of Community Health Sciences, University of Calgary, Alberta, Canada.
Am J Clin Nutr. 1994 Jan;59(1 Suppl):251S-252S. doi: 10.1093/ajcn/59.1.251S.
This paper presents the methodologic issues to consider when conducting a pooled analysis of data from nutritional epidemiologic studies. Because a wide variety of dietary assessment methods have been used in nutritional epidemiology, pooled analyses often combine data collected under very different circumstances. Whether these different methods influence the results obtained in a pooled analysis has not yet been examined. One of the main concerns in a pooled analysis is whether the data to be pooled are comparable. Questions to consider regarding data comparability and methods to address these questions in a pooled analysis are discussed.
本文介绍了在对营养流行病学研究数据进行汇总分析时需要考虑的方法学问题。由于营养流行病学中使用了各种各样的膳食评估方法,汇总分析常常会整合在非常不同的情况下收集的数据。这些不同的方法是否会影响汇总分析中获得的结果尚未得到检验。汇总分析中的一个主要问题是要汇总的数据是否具有可比性。本文讨论了关于数据可比性需要考虑的问题以及在汇总分析中解决这些问题的方法。