渗透压是肌动蛋白丝直径的主要决定因素。

Osmotic stress is the main determinant of the diameter of the actin filament.

作者信息

Grazi E, Schwienbacher C, Magri E

机构信息

Istituto di Chimica Biologica, Università di Ferrara, Italy.

出版信息

Biochem Biophys Res Commun. 1993 Dec 30;197(3):1377-81. doi: 10.1006/bbrc.1993.2629.

DOI:10.1006/bbrc.1993.2629

PMID:8280155

Abstract

The diameter of the actin filament is influenced by osmotic stress, being 9.0 nm at 1 x 10(5) dynes/cm2 and 6.8 nm at 9.00 x 10(6) dynes/cm2. At 1.81 x 10(5) dynes/cm2, the protein osmotic pressure in frog muscle, the diameter is 7.95 nm. The diameter of the tropomyosin-decorated actin filament is also influenced by osmotic stress even though, at the low pressures (up to 2 x 10(5) dynes/cm2), the decorated filament is significantly more resistant to compression than the undecorated actin filament.

摘要

肌动蛋白丝的直径受渗透压影响，在1×10⁵达因/平方厘米时为9.0纳米，在9.00×10⁶达因/平方厘米时为6.8纳米。在1.81×10⁵达因/平方厘米（青蛙肌肉中的蛋白质渗透压）时，直径为7.95纳米。原肌球蛋白修饰的肌动蛋白丝的直径也受渗透压影响，尽管在低压（高达2×10⁵达因/平方厘米）下，修饰的丝比未修饰的肌动蛋白丝对压缩的抵抗力明显更强。