Ishikawa A, Fukushima N, Takase A, Wagatsuma Y
Department of Pediatrics, Sapporo City General Hospital.
No To Hattatsu. 1994 Jan;26(1):20-5.
From 1986 to 1992, we examined 73 patients with severely mental and motor retardation. The onset age of 82% of the patients was less than one year. The number of patients was 29 and 54, in 1986 and 1992, respectively. The etiology for 48 patients was congenital or neonatal diseases. All patients were unable to eat by themselves. Tracheotomy was made on ten cases. Eight patients were on home oxygen therapy. Twenty-one patients had the history of mechanical ventilation. Sixty-three patients had the history of hospitalization and their total number of hospitalization was 343. About a half of hospitalizations was for respiratory disturbance. The number of cases with long term hospitalization recently increased. Ten patients died, only one patient died of pneumonia. Unexpected sudden death occurred in three patients.
1986年至1992年期间，我们对73例严重智力和运动发育迟缓患者进行了检查。82%的患者发病年龄小于1岁。1986年和1992年的患者人数分别为29例和54例。48例患者的病因是先天性或新生儿疾病。所有患者均无法自行进食。10例患者进行了气管切开术。8例患者接受家庭氧疗。21例患者有机械通气史。63例患者有住院史，其住院总次数为343次。约一半的住院是因为呼吸紊乱。近期长期住院的病例数有所增加。10例患者死亡，仅1例死于肺炎。3例患者发生意外猝死。
