Takano T, Matsui E, Yamano T, Shimada M, Okumura K
Department of Pediatrics, Shiga University of Medical Science, Ohtsu.
No To Hattatsu. 1994 Jan;26(1):63-7.
We report a two-year-old boy with clinical Reye syndrome. Brain CT disclosed symmetrical low-density areas in the pons and thalami, a part of which was recognized as being of high-intensity on both T1 and T2 weighted MRI. These lesions were suspected of being caused by vascular involvement, since the methemoglobin induced by bleeding may have contributed to the high-intensity regions. The lesions gradually disappeared within four months after the onset, and clinical symptoms also improved markedly without serious neurologic impairment. This case was characterized by the marked improvement in neurological and radiological findings in spite of the serious neurological involvement at onset.
我们报告了一名患有临床瑞氏综合征的两岁男孩。脑部CT显示脑桥和丘脑有对称的低密度区,其中一部分在T1加权和T2加权磁共振成像上均显示为高强度。这些病变怀疑是由血管受累引起的,因为出血诱导产生的高铁血红蛋白可能导致了高强度区域的出现。病变在发病后四个月内逐渐消失,临床症状也明显改善,未出现严重神经功能损害。尽管发病时神经受累严重,但该病例的特点是神经和影像学表现有显著改善。