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[利用单光子发射计算机断层扫描研究急性小儿偏瘫的脑灌注]

[Brain perfusion in acute infantile hemiplegia studied with single photon emission computed tomography].

作者信息

Tanaka Y, Nakanishi Y, Hamano S, Nara T, Aihara T

机构信息

Division of Neurology, Saitama Children's Medical Center.

出版信息

No To Hattatsu. 1994 Jan;26(1):68-73.

PMID:8280451
Abstract

Sequential examinations of single photon emission computed tomography (SPECT) were performed on a 5-month-old boy with acute infantile hemiplegia from the acute ictal stage. SPECT was performed with technetium-99m-hexamethyl-propylene-amineoxime during the status when the patient had left-hemiconvulsions (status epilepticus) and on the 3rd, 7th and 10th day after the status. During the ictal stage and the 3rd day after the status, diffuse hyperperfusion was revealed in the right hemisphere, while diffuse hypoperfusion was exhibited in the right hemisphere on the 7th and 10th day after the status. Hypoperfusion in the corresponding hemisphere, after the status, has been reported in patients with acute infantile hemiplegia. There has, however, been no report of ictal brain perfusion. The pathogenesis of this hyperperfusion is not clear, but alteration of brain perfusion in this patient, especially in acute phase, may help to elucidate the etiology of acute infantile hemiplegia.

摘要

对一名5个月大患急性婴儿偏瘫的男孩,从急性发作期开始进行单光子发射计算机断层扫描(SPECT)的连续检查。在患者出现左侧偏瘫(癫痫持续状态)时以及该状态后的第3、7和10天,使用锝-99m-六甲基丙烯胺肟进行SPECT检查。在发作期和状态后的第3天,右半球显示弥漫性血流灌注增加,而在状态后的第7天和第10天,右半球表现为弥漫性血流灌注减少。急性婴儿偏瘫患者在状态后相应半球出现血流灌注减少已有报道。然而,尚未有关于发作期脑灌注的报道。这种血流灌注增加的发病机制尚不清楚,但该患者脑灌注的改变,尤其是在急性期,可能有助于阐明急性婴儿偏瘫的病因。

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No To Hattatsu. 1994 Jan;26(1):68-73.
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