Botey J, Eseverri J L, Dordal M T, Andreu J, Marín A
Department of Allergy and Clinical Immunology, Vall d'Hebron Maternity and Children's Hospital, Barcelona, Spain.
J Investig Allergol Clin Immunol. 1993 Mar-Apr;3(2):100-2.
A variety of "hypoallergenic" formulas have appeared on the market over the last few years for feeding lactating infants prone to a high atopic risk of allergy to cow's milk. These formulas consist of soya preparations, hydrolyzed proteins and so-called basic formulas. This paper describes the main characteristics of such formulas, with particular emphasis on their tolerance, indications, related immunological aspects and antigenic capabilities. Notifications of anaphylactoid reactions with hydrolyzed proteins and the possibility of interactions with the IgE antibodies in cow's milk indicate such formulas in cases of non-IgE-mediated intolerance. Although soya preparations may be allergenic, they do not present interactions with the proteins in cow's milk; thus, they are particularly indicated in children with protein allergy to cow's milk with specific IgE antibodies.
在过去几年里，市场上出现了各种各样的“低敏”配方奶粉，用于喂养那些有对牛奶过敏的高特应性风险的哺乳期婴儿。这些配方奶粉包括大豆制品、水解蛋白和所谓的基础配方奶粉。本文描述了此类配方奶粉的主要特点，特别强调了它们的耐受性、适用症、相关免疫学方面以及抗原能力。关于水解蛋白类过敏样反应的报告以及与牛奶中IgE抗体相互作用的可能性表明，在非IgE介导的不耐受情况下可使用此类配方奶粉。尽管大豆制品可能具有致敏性，但它们不会与牛奶中的蛋白质发生相互作用；因此，它们特别适用于对牛奶蛋白过敏且有特异性IgE抗体的儿童。
