Indirect chelatometric determination of piperazine in some pharmaceutical preparations.

An indirect complexometric method is described for the determination of piperazine alone or in its pharmaceutical preparations. The method involves treatment of the aqueous solution of piperazine with carbon disulphide, ammonia solution and a known excess of cupric acetate, filtration of the formed precipitate and determination of the excess cupric acetate with EDTA using PAR as indicator.