Das Gupta V
Am J Hosp Pharm. 1976 Mar;33(3):283-4.
An assay for piperazine citrate in Piperazine Citrate Syrup USP is described. The assay method is based on the formation of a complex of piperazine with an acid dye, bromothymol blue. The complex can be extracted with chloroform and measured spectrophotometrically. The method is accurate and requires only 15 minutes for analysis, compared to four to five hours by the USP method.
本文描述了一种用于美国药典枸橼酸哌嗪糖浆中枸橼酸哌嗪的含量测定方法。该测定方法基于哌嗪与酸性染料溴麝香草酚蓝形成络合物。该络合物可用氯仿萃取并用分光光度法测定。该方法准确，与美国药典方法所需的四到五个小时相比，分析仅需15分钟。
