Brandberg A, Lindblom G B, Bartholdson L, Elgefors B
Scand J Plast Reconstr Surg. 1976;10(2):91-5. doi: 10.3109/02844317609105195.
The in-vitro antimicrobial effect of certain biological dressings was analysed. Glass basins lined with inverted human or pig skin treated and stored in various ways were inoculated with Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Glass basins served as controls. Human split skin from cadavers or living donors, deep frozen or preserved in Histocon and fresh-frozen pig had marked inhibitory activity. Heated skin and beta-irradiated pig skin did not have this effect. The antimicrobial effect was not observed during the first 2 hours of incubation but was present after 24 and 48 hours. It was not dependent on serum factors, It is concluded that when a biological dressings is used, advantage should be taken of its bactericidal activity, as infection is often a problem in sound dressing.
分析了某些生物敷料的体外抗菌效果。用金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌接种以各种方式处理和储存的内衬倒置人皮或猪皮的玻璃盆。玻璃盆作为对照。来自尸体或活体供体的人断层皮、深度冷冻或保存在组织保存液中的以及新鲜冷冻的猪皮具有显著的抑制活性。加热的皮肤和β射线照射的猪皮没有这种效果。在培养的最初2小时内未观察到抗菌效果，但在24小时和48小时后出现。它不依赖于血清因子。得出的结论是，当使用生物敷料时，应利用其杀菌活性，因为在合适的敷料中感染往往是一个问题。
