Rudolph F B
Institute of Biosciences and Bioengineering, Rice University, Houston, TX 77005.
J Nutr. 1994 Jan;124(1 Suppl):124S-127S. doi: 10.1093/jn/124.suppl_1.124S.
Nucleotides are phosphate esters of nucleosides that contain a sugar linked through a glycosidic linkage with purine and pyrimidine bases. Purine and pyrimidine nucleotides are major components of the cells that make up the monomeric units of DNA and RNA, and they function in all cellular processes. Biosynthesis, interconversion, catabolism and other aspects of nucleotide metabolism, along with various cellular roles of nucleotides, will be discussed, and the possible use of dietary sources of preformed purines and pyrimidines will be considered.
核苷酸是核苷的磷酸酯，其中的糖通过糖苷键与嘌呤和嘧啶碱基相连。嘌呤核苷酸和嘧啶核苷酸是构成DNA和RNA单体单元的细胞的主要成分，它们在所有细胞过程中发挥作用。本文将讨论核苷酸代谢的生物合成、相互转化、分解代谢及其他方面，以及核苷酸在细胞中的各种作用，并考虑预先形成的嘌呤和嘧啶的膳食来源的可能用途。
