Massengill S F, Richard G A, Donnelly W H
Department of Pediatrics, University of Florida, Gainesville 32610-0296.
J Pediatr. 1994 Jan;124(1):27-31. doi: 10.1016/s0022-3476(94)70250-0.
Two white female infants were seen with congenital nephrotic syndrome at age 6 weeks and 3 months, respectively. Both had hypocomplementemia, elevated antinuclear antibody and anti-double-stranded DNA titers, and diffuse proliferative glomerulonephritis with positive immunofluorescence in their initial renal biopsy samples. Although uncommon, infantile systemic lupus erythematosus should be considered in the evaluation of congenital nephrotic syndrome.
分别有两名白人女婴在6周龄和3月龄时被诊断为先天性肾病综合征。两人均有补体降低、抗核抗体和抗双链DNA滴度升高，且在初始肾活检样本中可见弥漫性增殖性肾小球肾炎伴免疫荧光阳性。尽管罕见，但在评估先天性肾病综合征时应考虑婴儿系统性红斑狼疮。
