Schulten E A, Starink T M, van der Waal I
Department of Oral & Maxillofacial Surgery and Oral Pathology, Free University Hospital, Academic Centre for Dentistry Amsterdam (ACTA), The Netherlands.
J Oral Pathol Med. 1993 Sep;22(8):374-7. doi: 10.1111/j.1600-0714.1993.tb01092.x.
Lichen sclerosus et atrophicus (LSA) is a relatively rare dermatosis of unknown etiology. The disease is clinically characterized by white, macular lesions on the skin, and is usually associated with an atrophic condition affecting the vulva and peri-anal skin. Involvement of the oral mucosa with or without concurrent genital or skin lesions has been reported only occasionally in the literature. In the present paper two new cases of oral LSA are presented, which were, in fact, the only manifestation of the disease. Furthermore, the epidemiologic, etiologic, clinical and histopathologic aspects of oral LSA are discussed.
硬化萎缩性苔藓(LSA)是一种病因不明的相对罕见的皮肤病。该病临床特征为皮肤上出现白色斑片状损害,通常伴有外阴及肛周皮肤萎缩。文献中仅偶尔报道过口腔黏膜受累,可伴有或不伴有生殖器或皮肤损害。本文报告了两例口腔LSA新病例,实际上这是该病的唯一表现。此外,还讨论了口腔LSA的流行病学、病因、临床及组织病理学方面。