Shibata T, Imoto I, Takaji S, Shima T
Third Department of Internal Medicine, Mie University School of Medicine.
Nihon Rinsho. 1993 Dec;51(12):3205-9.
The prevalence of H. pylori colonization in the antrum and body was examined in patients with gastritis, duodenal ulcer (DU) and gastric ulcer (GU). The total prevalence was 63.5%, 90.0% and 85.5%, respectively. In patients with gastritis and DU, the frequency was similar at both sites, while in GU patients H. pylori positivity was increased markedly in the body compared with the antrum. Furthermore, in patients with antral and angular ulcers, biopsy studies from 8 different sites showed that the H. pylori density score was significantly higher at the ulcer sites than at the non-ulcer sites. H. pylori infection is strongly implicated in the pathogenesis of gastritis and peptic ulceration.
在患有胃炎、十二指肠溃疡(DU)和胃溃疡(GU)的患者中,检测了幽门螺杆菌在胃窦和胃体的定植情况。总体患病率分别为63.5%、90.0%和85.5%。在胃炎和十二指肠溃疡患者中,两个部位的感染率相似,而在胃溃疡患者中,胃体部的幽门螺杆菌阳性率相比胃窦部显著升高。此外,在患有胃窦溃疡和角切迹溃疡的患者中,来自8个不同部位的活检研究表明,溃疡部位的幽门螺杆菌密度评分显著高于非溃疡部位。幽门螺杆菌感染与胃炎和消化性溃疡的发病机制密切相关。