Sandikci M U, Doran F, Koksal F, Sandikci S, Uluhan R, Varinli S, Akan E
Cukurova University Medical School, Department of Gastroenterology, Adana, Turkey.
Br J Clin Pract. 1993 Jul-Aug;47(4):187-9.
The presence of Helicobacter pylori (HP) in gastric biopsy specimens of 500 patients referred for routine upper gastrointestinal endoscopy for various abdominal complaints was investigated histologically and microbiologically. HP was detected in 429 of the 500 patients (86%). Antral biopsy specimens revealed gastritis in 457 out of 500 cases (91.4%). In the 43 patients who had normal histological findings, only 3 had HP infection (7%). The prevalence of HP in the patients with gastric and duodenal ulcers was 91%. In 95.6% of the ulcer patients, biopsy specimens showed gastritis. There was a statistically significant rise in the prevalence of HP with age. The correlation between histologic and microbiologic diagnostic methods was good. This study shows that HP positivity and gastritis are common in a routine endoscopy population and that there is a strong association between H. pylori, gastritis and peptic ulcer disease.
对500例因各种腹部不适接受常规上消化道内镜检查的患者的胃活检标本进行了组织学和微生物学检查，以调查幽门螺杆菌（HP）的存在情况。500例患者中有429例检测到HP（86%）。500例病例中有457例胃窦活检标本显示有胃炎（91.4%）。在43例组织学检查结果正常的患者中，只有3例有HP感染（7%）。胃溃疡和十二指肠溃疡患者中HP的患病率为91%。95.6%的溃疡患者活检标本显示有胃炎。HP的患病率随年龄增长有统计学意义的升高。组织学和微生物学诊断方法之间的相关性良好。本研究表明，在常规内镜检查人群中HP阳性和胃炎很常见，并且幽门螺杆菌、胃炎和消化性溃疡病之间存在密切关联。
