Ohtsu A, Yoshida S, Boku N, Fujii T, Oda Y, Miyata Y, Koba I, Muro K, Ohnaka O, Shimizu W
Department of Internal Medicine, National Cancer Center Hospital East, Kashiwa.
Jpn J Clin Oncol. 1993 Dec;23(6):373-7.
A case of esophageal small cell carcinoma with cervical node metastases and an esophago-mediastinal fistula was treated successfully by chemoradiotherapy. The fistula, after irradiation, was handled successfully by esophageal intubation, followed by infusional 5-fluorouracil and cisplatinum chemotherapy, resulting in the closure of the fistula. Two courses of concurrent chemoradiotherapy, followed by additional cisplatinum and etoposide chemotherapy, were administered. The tumor, including the cervical lymph node metastases, disappeared completely after the treatment.
一例伴有颈部淋巴结转移和食管纵隔瘘的食管小细胞癌患者通过放化疗成功治愈。放疗后，通过食管插管成功处理了瘘管，随后进行了5-氟尿嘧啶和顺铂的灌注化疗，使瘘管闭合。给予了两个疗程的同步放化疗，随后追加顺铂和依托泊苷化疗。治疗后，包括颈部淋巴结转移灶在内的肿瘤完全消失。
