Monakhov B V, Fedina V A, Chichua N A, Tsoĭ A I, Borisevich N V
Vopr Onkol. 1988;34(9):1114-8.
The effectiveness of polychemotherapy (platidiam + chemoradiation treatment) for extensive cancer of the esophagus, stomach and lung was studied in 71 patients. Response rate in esophageal cancer patients after platidiam, methotrexate and prospidin was 31%, which increased to 65% after irradiation. In stomach cancer patients treated with platidiam, 5-fluorouracil and vincristine, antitumor effect was registered in 30% and a 50% regression of tumor following radiotherapy--in 37%. In small cell lung cancer group, chemotherapy (platidiam + cyclophosphamide + vincristine) was effective in 37.5% and in 83% when combined with radiotherapy.
对71例广泛期食管癌、胃癌和肺癌患者研究了多药化疗（顺铂+放化疗）的疗效。食管癌患者接受顺铂、甲氨蝶呤和丙卡巴肼治疗后的缓解率为31%，放疗后升至65%。胃癌患者接受顺铂、5-氟尿嘧啶和长春新碱治疗后，30%出现抗肿瘤效果，放疗后肿瘤缩小50%的比例为37%。在小细胞肺癌组中，化疗（顺铂+环磷酰胺+长春新碱）的有效率为37.5%，联合放疗时有效率为83%。
