孤立性簇状微钙化：乳腺钼靶摄影的诊断价值——400例手术证实病例系列研究
Isolated clustered microcalcifications: diagnostic value of mammography--series of 400 cases with surgical verification.
作者信息
de Lafontan B, Daures J P, Salicru B, Eynius F, Mihura J, Rouanet P, Lamarque J L, Naja A, Pujol H
机构信息
Centre Claudius Regaud, Toulouse, France.
出版信息
Radiology. 1994 Feb;190(2):479-83. doi: 10.1148/radiology.190.2.8284403.
PURPOSE
To determine the diagnostic value of mammographic criteria in cases of isolated clustered microcalcifications.
MATERIALS AND METHODS
Four hundred mammographic studies of isolated clustered microcalcifications for which surgical verification was available were reviewed. A descriptive statistical study was performed to evaluate the distribution of each criterion relative to histopathologic results, followed by a multivariate study to determine statistically significant criteria. Seven breast specialists gave a consensus opinion on the need for surgery.
RESULTS
There were 302 benign lesions and 98 cancers. The most useful criteria were vermicular form, linear/branching shape, and irregular size of microcalcification. The number of biopsies recommended with use of these three criteria was 177 instead of the 172 recommended by the experts.
CONCLUSION
Use of these three preoperative criteria permits correct diagnosis of most such malignancies (90% in our series vs 67% diagnosed by the experts).
目的
确定乳腺钼靶检查标准在孤立性簇状微钙化病例中的诊断价值。
材料与方法
回顾了400例有手术验证的孤立性簇状微钙化的乳腺钼靶检查研究。进行描述性统计研究以评估各标准相对于组织病理学结果的分布，随后进行多变量研究以确定具有统计学意义的标准。七位乳腺专科医生就是否需要手术达成了共识。
结果
有302例良性病变和98例癌症。最有用的标准是蠕虫状形态、线性/分支状形状以及微钙化的不规则大小。使用这三个标准建议进行活检的数量为177例，而非专家建议的172例。
结论
使用这三个术前标准可对大多数此类恶性肿瘤做出正确诊断（我们的系列研究中为90%，而专家诊断为67%）。
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